李小康 Li Xiaokang
教授/总裁助理/主任医师

第四军医大学骨外科学博士,现任陕西泰发祥集团有限公司总裁助理,主任 医生。2025 年加入 BEBC,担任兼职教授。主要研究方向为骨肿瘤与骨缺损修复、3D 打印个性 假体。已在 Prog Mater Sci 、Trends Cancer、Bioact. Mater 等国际知名期刊上发表 SCI 论文 13 篇。
研究方向: 骨肿瘤与骨缺损修复、3D 打印个性假体
教育经历:
2019.08-2019.10 美国加州大学洛杉矶分校(UCLA) ,访问学者
2012.11-2013.01 新加坡南洋理工大学,访问学者
2010.09-2013.07 第四军医大学,骨外科学,博士
2007.09-2010.07 第四军医大学,骨外科学,硕士
2002.09-2007.07 第四军医大学,临床医学,本科生
工作经历:
2024.01-2025.07 唐都医院,主任医师
2021.10-2024.01 唐都医院,副主任医师
2019.01-2021.09 西京医院,副主任医师
2013.07-2018.12 西京医院,主治医师/讲师
代表性著作:
1. Wang H#, Yang Y#, Zhou X#, Tian J#, Duan X, LiA, Lu TJ*, Li X*, Pei D*, Xu F*.Rational design of mechanical bio-metamaterials for biomedical applications. Prog Mater Sci, 2025, 156: 101545.(IF 40.00 ,1 区)
2. Ouyang P, Cheng B, He X*, Lou J*, Li X*, Guo H*, Xu F*. Navigating the biophysical landscape: how physical cues steer the journey of bone metastatic tumor cells. Trends Cancer, 2024, 10: 792-808.(IF 17.50 ,1 区)
3. Wu H#, Wei X#, Liu Y#, Dong H, Tang Z, Wang N, Bao S, Wu Z, ShiL, Zheng X, Li X*, Guo Z*. Dynamic degradation patterns of porous polycaprolactone/β- tricalcium phosphate composites orchestrate macrophage responses and immunoregulatory bone regeneration. Bioact Mater, 2023, 21: 595-611.(IF 20.30,1 区)
4. Bao S#, Yu D#, Tang Z#, Wu H, Zhang H, Wang N, Liu Y, Huang H, Liu C*, Li X*, Guo Z*. Conformationally regulated “nanozyme-like” cerium oxide with multiple free radical scavenging activities for osteoimmunology modulation and vascularized osseointegratio. Bioact Mater, 2024, 34: 64-79.(IF 20.30 ,1 区)
5. Wei X#, Zhou W#, Tang Z#, Wu H, Liu Y, Dong H, Wang N, Huang H, Bao S, Shi L, Li X*, Zheng Y*, Guo Z*. Magnesium surface-activated 3D printed porous PEEK scaffolds for in vivo osseointegration by promoting angiogenesis and osteogenesi. Bioact Mater, 2023, 20: 16-28.(IF 20.30 ,1 区)
6. Wu H#, Dong H#, Tang Z#, Chen Y, Liu Y, Wang M, WeiX, Wang N, Bao S, Yu D, Wu Z, Yang Z, Li X*, Guo Z*, Shi L*. Electrical stimulation of piezoelectric BaTiO3 coated Ti6Al4V scaffolds promotes anti-inflammatory polarization of macrophages and bone repair via MAPK/JNK inhibition and OXPHOS activatio. Biomaterials, 2023, 293: 121990.(IF 12.90 ,1 区)
7. Wang N#, Liu X, Tang Z, WeiX, Dong H, Liu Y, Wu H, Wu Z, Li X*, Ma X*, Guo Z*. Increased BMSC exosomal miR-140-3p alleviates bone degradation and promotes bone restoration by targeting Plxnb1 in diabetic rats. J Nanobiotechnology, 2022, 20: 97.(IF 12.60 ,1 区)
8. Yu D#, Tang Z, Bao S, Guo S, Chen C, Wu Q, Wang M, Zheng Z, Cao P, Xu B, Wu H, Wang N, Huang H, Liu C*, Li X*, Guo Z*. Immunoregulatory neuro- vascularized osseointegration driven by different nano-morphological CaTiO3 bioactive coatings on porous titanium alloy scaffolds. Adv Healthc Mater, 2025, 14: 2404647.(IF 9.60 ,2 区)
9. Zheng Z#, Yu D#, Wang H#, Wu H, Tang Z, Wu Q, Cao P, Chen Z, Huang H, Li X*, Liu C*, Guo Z*. Advancement of 3D biofabrication in repairing and regeneration of cartilage defects. Biofabrication, 2025, 17: 022003.(IF 8.00 ,2 区)
10. Tang Z#, Yu D, Bao S, Li C, Wu H, Dong H, Wang N, Liu Y, Wu Q, Chen C, Wang M, Cao P, Zheng Z, Huang H, Li X*, Guo Z*. Porous titanium scaffolds with mechanoelectrical conversion and photothermal function: A win ‐win strategy for bone reconstruction of tumor ‐resected defects. Adv Healthc Mater, 2024, 13: 2302901.(IF 9.60 ,2 区)
11. Liu W#, Li X#, Jiao Y#, Wu C, Guo S, Xiao X, WeiX, Wu J, Gao P, Wang N, Lu Y, Tang Z, Zhao Q, Zhang J, Tang Y*, Shi L*, Guo Z*. Biological effects of a three- dimensionally printed Ti6Al4V scaffold coated with piezoelectric BaTiO3 nanoparticles on bone formation. ACS Appl Mater Interfaces, 2020, 12: 51885- 51903.(IF 8.20 ,2 区)
12. Yu D#, Guo S#, Yu M#, Liu W, Li X, Chen D, Li B*, Guo Z*, Han Y*. Immunomodulation and osseointegration activities of Na2TiO3 nanorods-arrayed coatings doped with different Sr content. Bioact Mater, 2022, 10: 323-334.(IF 20.30 ,1 区)
13. Jia Y, Feng J, Feng Z, Liu J, Yang Y, Li X, Lei M, Guo H, Wei Z*, LvY*, Xu F*. An endoscopically compatible fast-gelation powder forms Janus-adhesive hydrogel barrier to prevent postoperative adhesions. Proc Natl Acad Sci, 2023, 120: e2219024120(IF 9.10 ,1 区)