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Congratulations to Xiayu Xu for her paper published in Biomedical Optics Express

2018/07/16      view:

Recently, Dr. Xiayu Xu from BEBC has published her first author paper in Biomedical Optics Express entitled " Simultaneous arteriole and venule segmentation with domain-specific loss function on a new public database ".


Abstract graph of this study

In this paper, they studied the segmentation and classification of retinal arterioles and venules which play an important role in the diagnosis of various eye diseases and systemic diseases. The major challenges include complicated vessel structure, inhomogeneous illumination, and large background variation across subjects. In this study, they employ a fully convolutional network to simultaneously segment arterioles and venules directly from the retinal image, rather than using a vessel segmentation-arteriovenous classification strategy as reported in most literature. To simultaneously segment retinal arterioles and venules, we configured the fully convolutional network to allow true color image as input and multiple labels as output. A domain-specific loss function was designed to improve the overall performance. The proposed method was assessed extensively on public data sets and compared with the stateof-the-art methods in literature. The sensitivity and specificity of overall vessel segmentation on DRIVE is 0.944 and 0.955 with a misclassification rate of 10.3% and 9.6% for arteriole and venule, respectively. The proposed method outperformed the state-of-the-art methods and avoided possible error-propagation as in the segmentation-classification strategy. The proposed method was further validated on a new database consisting of retinal images of different qualities and diseases. The proposed method holds great potential for the diagnostics and screening of various eye diseases and systemic diseases.
The co-authors of the paper include Rendong Wang, PeiLin Lv, Bin Gao, Chan Li, ZhiQiang Tian, Tao Tan and Feng Xu.